Understanding Phenacetin Powder (CAS 62-44-2) and Its Suppliers

Phenacetin, identifiable by its CAS number 62-44-2, is a pharmaceutical compound that has historically been utilized for its analgesic and antipyretic properties. It belongs to the category of non-opioid analgesics and is structurally related to paracetamol (acetaminophen). Although its usage has significantly declined due to safety concerns, it is still essential to understand the characteristics of this compound, its historical significance, and the landscape of suppliers in the market today.

Historical Context of Phenacetin

Phenacetin was first introduced in the late 19th century and became widely used in the early 20th century. It was primarily employed to alleviate pain and reduce fever. Its application included treatment for headaches, muscle pain, and other mild to moderate aches. However, over the years, concerns regarding its safety profile led to a decline in its use. The compound has been associated with various adverse effects, including nephropathy (kidney damage) and potential carcinogenic properties. As a result, many countries have banned or restricted its use in over-the-counter medications.

Despite these concerns, phenacetin remains of interest in research and certain industrial applications. It serves as a precursor in the synthesis of other pharmaceutical compounds and chemicals, prompting a maintained demand for its procurement in controlled settings.

Features and Properties

Phenacetin appears as a white crystalline powder, showcasing solubility in organic solvents like alcohol while being poorly soluble in water. Its chemical formula is CnH13N3O2, and it has a molecular weight of 179.22 g/mol. The compound is often produced through the esterification of ethyl paraben with an amine, yielding phenacetin in a series of chemical reactions.

One significant consideration in the procurement of phenacetin powder is purity. Suppliers typically provide specifications regarding the purity level, which is crucial for research and industrial applications. High-purity phenacetin is essential to avoid interference in experimental results and ensure safety in subsequent applications.

The market for phenacetin powder has become more specialized, with suppliers focusing on high-quality production methods and stringent quality control measures. When searching for a reliable phenacetin supplier, several factors should be considered

1. Regulatory Compliance Ensure that the supplier adheres to the regulatory standards set by health authorities, such as the FDA or EMA. This compliance ensures that the product is produced in a controlled environment, reducing the risk of contamination.

2. Quality Assurance Look for suppliers who offer certificates of analysis (CoA) for their products. This documentation should confirm the purity and quality of the phenacetin powder, helping you make an informed decision.

3. Reputation and Reviews Supplier reputation is paramount. Research online reviews and testimonials to gauge the reliability of a supplier. Established suppliers often have a history of delivering quality products and exemplary customer service.

4. Pricing and Availability While cost is an important factor, it should not be the only one considered. Compare prices from multiple suppliers but prioritize quality over the lowest price to avoid compromising on safety and efficacy.

5. Technical Support Suppliers who provide additional resources, such as technical data sheets, application guides, or responsive customer service, can enhance your purchasing experience and ensure you have the necessary information for your specific application.

Conclusion

Phenacetin powder (CAS 62-44-2) has a complex history marked by its initial popularity and later restrictions due to safety concerns. While its use in mainstream medicine has decreased, the demand for phenacetin remains in research and specific industrial sectors. Identifying a reputable supplier is crucial for researchers and manufacturers who require phenacetin for their projects. By considering regulatory compliance, quality assurance, supplier reputation, pricing, and available support, stakeholders can procure high-quality phenacetin that meets their needs safely and effectively.