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ഡിസം . 07, 2024 05:37 Back to list

cas 1379686-29-9 sr-9011



Exploring CAS 1379686-29-9 SR-9011 and Its Implications in Research and Medicine


CAS number 1379686-29-9 refers to SR-9011, a synthetic compound that has gained attention in recent years for its intriguing effects on metabolism and potential applications in various fields of research. As an SR9009 analogue, SR-9011 shares significant similarities, notably its ability to modulate the Rev-Erb family of nuclear receptors. This article delves into the properties of SR-9011, its mechanisms of action, and its potential applications in medicine and beyond.


Understanding SR-9011

SR-9011 is a small molecule that functions primarily as a selective agonist for the Rev-Erb receptors, particularly Rev-Erbα and Rev-Erbβ. These nuclear receptors play pivotal roles in regulating circadian rhythms, metabolism, and inflammatory responses. The ability of SR-9011 to influence these receptors suggests that it could have profound effects on energy homeostasis and metabolic disorders.


One of the most striking features of SR-9011 is its capability to enhance the metabolic rate and improve endurance in animal studies. By activating Rev-Erb receptors, SR-9011 has been shown to increase the utilization of fat stores, decrease fat mass, and improve glucose tolerance. This metabolic enhancement has drawn interest for potential implications in treating obesity, type 2 diabetes, and other metabolic conditions.


Mechanisms of Action


The mechanism by which SR-9011 exerts its effects primarily involves modulation of gene expression through Rev-Erb receptors. When SR-9011 binds to these receptors, it alters the transcription of genes involved in fatty acid metabolism, circadian rhythm regulation, and inflammation. This modulation is crucial for maintaining metabolic homeostasis and may offer insights into how to combat metabolic syndrome.


cas 1379686-29-9 sr-9011

cas 1379686-29-9 sr-9011

Additionally, SR-9011 has been observed to influence the biological clock, thereby affecting sleep, energy balance, and overall health. Circadian rhythms dictate not just sleep-wake cycles but also the timing of metabolic processes. By fine-tuning these rhythms, SR-9011 presents a unique avenue for therapeutic interventions that address not only metabolic diseases but also sleep disorders and related conditions.


Research and Clinical Implications


The potential of SR-9011 extends far beyond basic metabolic enhancement. Researchers are exploring its implications in various areas, including aging, cancer, and cardiovascular diseases. The compound's ability to regulate inflammation could make it a candidate for treating chronic inflammatory conditions. Furthermore, its influence on cellular metabolism may have ramifications for understanding cancer cell growth and survival, as many tumors exhibit altered metabolic pathways.


Despite the promising results observed in preclinical studies, the translation of these findings to human applications remains a significant challenge. Clinical trials are essential to assess the safety, efficacy, and appropriate dosing of SR-9011 in humans. As the research progresses, it will be crucial to consider the long-term effects and potential side effects associated with its use.


Conclusion


In summary, CAS 1379686-29-9, or SR-9011, represents a fascinating compound with potential implications for metabolic health and beyond. Its ability to modulate Rev-Erb receptors highlights an innovative approach to addressing metabolic disorders, circadian rhythm disturbances, and possibly various chronic diseases. As research continues to unfold, SR-9011 may emerge as a pivotal player in the next generation of therapeutics aimed at enhancing healthspan and combating metabolic syndromes. However, rigorous clinical trials will be vital to ensure that its benefits can be safely harnessed in clinical practices. The journey of SR-9011 from the laboratory to potential therapeutic use underscores the importance of continued research in the field of biomedicine.


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