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Сеп . 16, 2024 06:43 Back to list

O-Benzylhydroxylamine Hydrochloride (CAS 2687-43-6) Manufacturer



O-Benzylhydroxylamine Hydrochloride A Key Intermediate in Pharmaceutical Chemistry


O-benzylhydroxylamine hydrochloride, with the CAS number 2687-43-6, is a significant chemical compound widely utilized in pharmaceutical research and development. It serves as an important intermediate in the synthesis of various bioactive molecules and plays a vital role in the development of novel therapeutics.


Chemical Structure and Properties


O-benzylhydroxylamine hydrochloride is characterized by its unique chemical structure, which includes a hydroxylamine functional group (-NH2OH) and a benzyl substituent (C6H5CH2-). This structural design imparts distinctive chemical properties that facilitate its reactivity in various organic reactions. The compound generally appears as a white crystalline solid and is soluble in water, making it a practical choice for many laboratory applications.


Synthesis and Production


The production of O-benzylhydroxylamine hydrochloride involves several synthetic pathways. One common method includes the reaction of benzyl bromide with hydroxylamine in the presence of a suitable base. This reaction not only yields the desired product but also generates a byproduct that can be easily separated. Given the need for high purity, manufacturers often employ advanced purification techniques such as recrystallization or chromatography to eliminate impurities and ensure that the final product meets the stringent quality standards required for pharmaceutical applications.


Applications in Pharmaceutical Chemistry


o-benzylhydroxylamine hydrochloride cas 2687-43-6 manufacturer

o-benzylhydroxylamine hydrochloride cas 2687-43-6 manufacturer

O-benzylhydroxylamine hydrochloride is primarily recognized for its utility in the synthesis of oxime derivatives, which are pivotal in medicinal chemistry. Oximes are crucial in developing various pharmaceuticals, including anti-infectives, antihypertensives, and anticancer agents. The versatility of O-benzylhydroxylamine allows chemists to modify core structures efficiently, promoting the discovery of new therapeutic agents with enhanced efficacy and reduced side effects.


Moreover, O-benzylhydroxylamine hydrochloride has been employed in the modification of complex natural products, paving the way for the development of innovative drugs. Its reactivity and ability to form stable intermediates make it a valuable asset in pharmaceutical research. The compound's effectiveness is further highlighted by its role in elucidating biochemical pathways, where it acts as a reagent to investigate the mechanisms of various enzymatic reactions.


Regulatory Considerations and Safety


As with any chemical compound used in drug development, the safety and regulatory aspects of O-benzylhydroxylamine hydrochloride are paramount. Manufacturers must comply with Good Manufacturing Practices (GMP) to ensure the consistency and quality of the product. Additionally, safety data sheets (SDS) are essential to inform handling and storage procedures, protecting laboratory personnel from potential hazards when dealing with this compound.


Conclusion


In conclusion, O-benzylhydroxylamine hydrochloride is a key intermediate in the pharmaceutical industry, facilitating the synthesis of important oxime derivatives and contributing to the advancement of therapeutic agents. Its unique properties, combined with safe manufacturing processes and regulatory compliance, underscore its significance in modern medicinal chemistry. As research continues to evolve, the role of O-benzylhydroxylamine hydrochloride in drug discovery is expected to expand, leading to new and innovative treatments for various diseases.


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