Understanding Wholesale Phenacetin Powder CAS 62-44-2

Phenacetin, with the chemical formula C8H9NO2 and CAS number 62-44-2, is a compound that has garnered considerable attention in pharmaceutical and chemical industries. Historically significant as a pain-relieving and antipyretic agent, phenacetin is a white crystalline powder often available in bulk for pharmaceutical formulations. However, its profile as a medication has evolved considerably, leading to shifts in its regulation and use.

Historical Background

Phenacetin was first synthesized in the late 19th century and became widely used due to its efficacy in treating pains, fevers, and mild headaches. It was favored as a non-opioid analgesic and gained popularity for its relatively low side effects compared to other analgesics of the time. However, as research progressed, concerns regarding its safety emerged. Studies indicated that long-term use of phenacetin was associated with renal toxicity and a potential link to carcinogenesis, leading to its withdrawal from most markets and the reassessment of its clinical application.

Chemical Properties

Phenacetin belongs to the class of compounds known as anilides. It features an acetamide group, which contributes to its analgesic properties. It is practically insoluble in water but soluble in organic solvents such as ethanol and chloroform. These properties make it suitable for specific pharmaceutical applications, particularly in formulations where solubility in organic mediums is required.

Despite its historical medical use being largely curtailed, phenacetin still finds a role in various industrial applications, especially in the production of other chemical compounds. Companies involved in the synthesis of pharmaceuticals often purchase phenacetin in wholesale quantities as it serves as an intermediate in the production of other analgesics, such as paracetamol (acetaminophen), which remains widely used today.

In the laboratory, phenacetin is utilized in organic synthesis and chemical research. Its properties as a reagent make it valuable for creating more complex chemical entities. Industrial manufacturers can source wholesale phenacetin powder from suppliers specializing in bulk chemical distribution. This allows them to maintain production efficiency while ensuring cost-effectiveness.

Health and Safety Considerations

While wholesale phenacetin powder is available for legitimate uses, it is crucial to handle it with care. The compound is classified as a potential human carcinogen, and exposure should be minimized. Adequate safety measures must be employed while handling this chemical, including the use of personal protective equipment (PPE) like gloves, goggles, and lab coats. Furthermore, it is essential to follow all relevant guidelines from regulatory bodies such as the Occupational Safety and Health Administration (OSHA) and the Environmental Protection Agency (EPA) in the United States when working with this substance.

Market Dynamics

The market for wholesale phenacetin powder is influenced by several factors, including the demand for alternative pain management therapies, innovations in pharmaceutical formulations, and regulatory changes that impact the use of various analgesics. Pricing varies, with bulk purchases often leading to significant savings for manufacturers. Suppliers typically offer different grades of phenacetin, and buyers should ensure they source from reputable vendors that provide product specifications and safety data sheets.

Conclusion

In summary, while wholesale phenacetin powder (CAS 62-44-2) has seen a decline in its direct use as a medical drug due to safety concerns, it remains a vital component in certain chemical and pharmaceutical industries. Understanding its properties and applications is essential for manufacturers and researchers engaging in synthetic chemistry. As the landscape of pharmaceuticals continues to evolve, phenacetin’s relevance may transform, underscoring the dynamic nature of chemical usage in industry and research. Proper handling, adherence to safety regulations, and informed purchasing decisions will ensure responsible use of this historically significant compound.