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តុលា . 31, 2024 23:36 Back to list

Phenacetin Powder CAS 62-44-2 for Pharmaceutical Applications and Research Uses



Phenacetin Powder An Overview of Its Uses and Implications


Phenacetin, with the Chemical Abstracts Service (CAS) number 62-44-2, is a synthetic compound that belongs to the class of analgesics and antipyretics. Historically, it was widely used in the pharmaceutical industry for its pain-relieving and fever-reducing properties. However, its usage has diminished over the years due to safety concerns, particularly its association with renal damage and the potential for causing cancer.


Phenacetin Powder An Overview of Its Uses and Implications

Phenacetin's popularity began to wane in the mid-20th century as studies emerged indicating serious health risks. Research in the 1970s linked long-term use of phenacetin to analgesic nephropathy, a condition characterized by damage to the kidneys caused by prolonged use of pain medications. Furthermore, findings suggested a potential association with certain cancers, particularly bladder cancer, leading to increased scrutiny and regulatory action against its use.


china phenacitin powder cas 62-44-2

china phenacitin powder cas 62-44-2

Due to these concerns, many countries have taken steps to ban or restrict the sale and distribution of phenacetin. For instance, in the United States, the Food and Drug Administration (FDA) prohibited the use of phenacetin in pharmaceutical formulations in the late 1980s. Despite its reduction in pharmaceutical applications, phenacetin is still available in some areas as a research chemical or for use in laboratories.


In recent years, while phenacetin's role in medicine has been largely supplanted by safer alternatives such as acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs), it remains of interest in the field of chemical research. Studies focusing on its metabolism, the biochemical pathways it influences, and the mechanisms behind its side effects continue to be relevant. Researchers are particularly interested in how this compound interacts with human biochemistry, contributing to a greater understanding of drug interactions and the risks involved with analgesic medications.


Despite its controversial history, phenacetin serves as a reminder of the importance of drug safety and the rigorous testing required before substances can be deemed safe for public consumption. The challenges faced in the past underscore the necessity for ongoing pharmacovigilance—monitoring the safety of medications after they have been released onto the market.


In summary, phenacetin (CAS 62-44-2) is a compound that has played a significant role in the history of analgesics. Although its use has largely been eclipsed by safer alternatives due to health risks, its legacy contributes to the broader conversation about drug safety and the evolution of healthcare practices. Understanding past substances like phenacetin can inform better decision-making and regulatory frameworks for current and future medications.


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