Tetramisole Hydrochloride An Overview of Manufacturers and Applications

Tetramisole hydrochloride, a chemical compound with the CAS number 50586-74-8, is primarily used as an anthelmintic agent in both veterinary and human medicine. Originally developed as a deworming treatment, it is now also recognized for its immunomodulatory properties, which have expanded its applications in various fields. The demand for this compound in medical and agricultural sectors has led to the emergence of several manufacturers globally.

Understanding Tetramisole Hydrochloride

Tetramisole hydrochloride belongs to the imidazothiazole class of drugs and operates by inhibiting muscle function in parasites, leading to their expulsion from the host's body. Its effectiveness against a broad spectrum of parasitic infections makes it valuable, particularly in veterinary medicine, where it is often administered to livestock. In humans, tetramisole has been used to treat certain types of worm infections, but its usage has declined in favor of newer alternatives over the years.

Therapeutic and Agricultural Applications

In addition to its role as an anthelmintic, tetramisole demonstrates potential as an immunostimulant. Research indicates that it might enhance the immune response, which can be beneficial in treating various diseases. This property has garnered interest from pharmaceutical manufacturers exploring its applications in cancer treatment and autoimmune diseases.

In agriculture, tetramisole is used to improve the health of livestock by ensuring they remain parasite-free, boosting productivity in meat and dairy production. Its role in agriculture extends to being a feed additive, enhancing overall animal health and productivity. Furthermore, its formulation in pesticides has been explored due to its effectiveness against specific pests.

Major Manufacturers

A number of manufacturers around the world specialize in the production of tetramisole hydrochloride. These companies are pivotal in supplying this compound to pharmaceutical and agricultural sectors. Some prominent manufacturers include

1. Hubei Yichang Humanwell Pharmaceutical Co., Ltd. - Located in China, this company is known for producing a variety of pharmaceutical chemicals, including tetramisole hydrochloride. Their commitment to quality and safety standards has made them a trusted source in the industry.

2. Jiangsu Tiansheng Pharmaceutical Co., Ltd. - Specializing in veterinary medicines, this manufacturer produces tetramisole hydrochloride in compliance with international regulations, focusing on both efficacy and safety for animal health applications.

3. Hunan Lijian Pharmaceutical Co., Ltd. - Also based in China, Lijian Pharmaceutical supplies tetramisole hydrochloride for both human and veterinary use, catering to a diverse clientele while adhering to stringent quality control measures.

4. Sigma-Aldrich (Merck Group) - A well-known name in the chemical and pharmaceutical industry, Sigma-Aldrich offers high-quality tetramisole hydrochloride, particularly aimed at research and industrial applications globally.

Quality Control and Regulatory Compliance

Manufacturers of tetramisole hydrochloride undergo rigorous quality control processes to ensure that their products meet the required standards. Compliance with Good Manufacturing Practices (GMP) and local regulatory requirements is crucial. The global market for tetramisole hydrochloride is guided by regulations from organizations such as the FDA (Food and Drug Administration) in the U.S. and EMA (European Medicines Agency) in Europe, which oversee the pharmaceutical compliance and safety of products reaching consumers.

Conclusion

In summary, tetramisole hydrochloride, identified by CAS number 50586-74-8, plays a vital role in both human and veterinary medicine. Its multifaceted applications, alongside its importance in maintaining livestock health, underscore the significance of its production. With various manufacturers engaged in its production and research exploring its potential, tetramisole hydrochloride remains a critical compound in pharmaceutical and agricultural sectors. As the landscape of healthcare continues to evolve, the role of such compounds in disease management and animal husbandry will likely expand further, promoting the well-being of both humans and animals.