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Dec . 23, 2024 07:32 Back to list

38191-34-3



The compound with the CAS Number 38191-34-3 is commonly known as Hepatocyte Growth Factor (HGF). This protein plays a vital role in various biological processes, particularly in liver regeneration, cell proliferation, and angiogenesis. HGF is initially synthesized as an inactive precursor, which is then activated enzymatically to exert its physiological effects. Its significance spans across numerous fields of research, including developmental biology, oncology, and regenerative medicine.

HGF is primarily produced by mesenchymal cells, particularly fibroblasts, and plays a critical role in organ development and tissue repair. One of its most notable functions is promoting liver regeneration after injury. When the liver is damaged, HGF stimulates the proliferation of hepatocytes, the main functional cells of the liver, thus facilitating the repair process. This regenerative capability is essential, especially considering the increasing incidence of liver diseases worldwide, such as cirrhosis and hepatic failure.


The compound with the CAS Number 38191-34-3 is commonly known as Hepatocyte Growth Factor (HGF)

. This protein plays a vital role in various biological processes, particularly in liver regeneration, cell proliferation, and angiogenesis. HGF is initially synthesized as an inactive precursor, which is then activated enzymatically to exert its physiological effects. Its significance spans across numerous fields of research, including developmental biology, oncology, and regenerative medicine.


From an oncology perspective, the increased expression of HGF and c-Met has been implicated in various types of cancers. Tumors often hijack the HGF/c-Met signaling pathway to enhance their growth, invasion, and metastasis. Consequently, understanding the mechanisms of HGF can provide insights into cancer progression and potential therapeutic targets. Researchers have explored the development of c-Met inhibitors as a novel approach to treating specific cancers, indicating the dual role of HGF in both promoting healthy tissue regeneration and facilitating cancer progression.


38191-34-3

<trp-post-container data-trp-post-id='18428'>38191-34-3</trp-post-container>

The therapeutic potential of HGF extends beyond cancer treatment. Its regenerative properties have garnered interest in the field of regenerative medicine, where scientists are investigating its use in various applications, including tissue engineering and stem cell therapy. By harnessing the power of HGF, researchers aim to develop strategies for repairing damaged tissues and organs, leading to advancements in treatments for conditions like myocardial infarction, neurodegenerative diseases, and chronic wounds.


Moreover, the development of HGF-based therapies stands to revolutionize how we approach healing and regeneration. For instance, studies have shown the promising effects of HGF in enhancing the survival and integration of transplanted cells, which could improve the outcomes of cell therapies for conditions such as diabetes and heart disease.


In conclusion, HGF (CAS 38191-34-3) is a multifaceted growth factor with profound implications in both health and disease. Its pivotal roles in liver regeneration, cancer biology, and tissue repair make it a significant focus of research across various scientific domains. As our understanding of HGF deepens, it holds the promise of unlocking new therapeutic avenues that could transform the landscape of modern medicine, improving patient outcomes and enhancing the quality of care across myriad conditions. The ongoing exploration of HGF signifies a critical step toward harnessing the body’s natural healing capabilities in the face of injury and disease.


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