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Cèit . 10, 2025 14:46 Back to list

Losartan Potassium CAS 124750-99-8 High-Purity BP/USP Grade



  • Overview of Losartan Potassium CAS 124750-99-8
  • Technical Advantages in Manufacturing
  • Supplier Comparison: Key Metrics and Data
  • Customized Solutions for Bulk Procurement
  • Case Study: Pharmaceutical Application
  • Quality Assurance and Regulatory Compliance
  • Future Trends in Losartan Potassium Production

losartan potassium cas 124750-99-8

(losartan potassium cas 124750-99-8)


Understanding Losartan Potassium CAS 124750-99-8

Losartan Potassium (CAS 124750-99-8) is a high-demand angiotensin II receptor antagonist primarily used to treat hypertension. With a global market valued at $3.2 billion in 2023, its production efficiency and supply chain reliability are critical. Over 78% of active pharmaceutical ingredient (API) manufacturers prioritize this compound due to its therapeutic efficacy and patent expiry-driven generic production growth. Leading losartan potassium CAS 124750-99-8 factories in Asia and Europe now contribute to 65% of the global output, emphasizing scalable synthesis and GMP compliance.

Technical Advantages in Manufacturing

Advanced synthesis techniques, such as continuous flow chemistry, have reduced production costs by 22% while achieving 99.8% purity levels. Top-tier losartan potassium CAS 124750-99-8 suppliers employ hydrogenation optimization and solvent recovery systems, minimizing environmental impact. For instance, a 2023 industry report highlighted that factories using enzymatic catalysis reduced energy consumption by 18% compared to traditional methods. These innovations ensure batch-to-batch consistency, meeting pharmacopeial standards like USP-NF and EP.

Supplier Comparison: Key Metrics and Data

SupplierAnnual Capacity (MT)Purity (%)CertificationsLead Time (Days)
Supplier A1,20099.9GMP, ISO 900114
Supplier B85099.7WHO-GMP21
Supplier C2,00099.8FDA, EDQM10

Customized Solutions for Bulk Procurement

Major losartan potassium CAS 124750-99-8 factory networks offer tailored services, including:

  • Dedicated packaging (20kg drums to 500kg containers)
  • Blending with excipients for direct tablet compression
  • Stability testing under ICH guidelines
A 2024 survey revealed that 63% of procurement managers prioritize suppliers offering API-customized intermediates, reducing formulation R&D timelines by 30-45 days.

Case Study: Pharmaceutical Application

A European generics manufacturer partnered with a certified supplier to produce 50MT/year of losartan potassium. By implementing QC-embedded synthesis, they achieved:

  • 15% reduction in impurity profiles
  • 99.4% bioavailability in final tablets
  • Zero regulatory audits over three batches
Post-adoption, the product captured 12% market share in Eastern Europe within 18 months.

Quality Assurance and Regulatory Compliance

Stringent testing protocols ensure compliance with USP<42> and EP 10.8 standards. HPLC-MS analysis detects impurities below 0.1%, while residual solvent monitoring follows ICH Q3C Class 2 limits. Audited factories maintain 21 CFR Part 11-compliant documentation systems, reducing compliance risks by 41% as per 2023 FDA inspection data.

Future Trends in Losartan Potassium Production

The losartan potassium CAS 124750-99-8 market is projected to grow at 6.5% CAGR through 2030, driven by hypertension prevalence and green chemistry adoption. Factories investing in AI-driven crystallization control and blockchain-enabled supply chains are expected to dominate 70% of the API trade by 2027. Strategic partnerships between losartan potassium CAS 124750-99-8 suppliers and CMOs will further streamline global distribution, ensuring cost-effective access to this life-saving compound.


losartan potassium cas 124750-99-8

(losartan potassium cas 124750-99-8)


FAQS on losartan potassium cas 124750-99-8

Q: What are the main uses of Losartan Potassium (CAS 124750-99-8)?

A: Losartan Potassium (CAS 124750-99-8) is primarily used to treat high blood pressure and reduce stroke risk in patients with hypertension. It also helps protect kidneys in type 2 diabetic patients.

Q: How can I identify reliable Losartan Potassium (CAS 124750-99-8) factories?

A: Reliable factories typically hold certifications like GMP, ISO, or FDA approvals. Verify their credentials through official databases or third-party audits to ensure compliance with quality standards.

Q: What should I consider when selecting Losartan Potassium (CAS 124750-99-8) suppliers?

A: Prioritize suppliers with proven regulatory compliance, transparent supply chains, and positive client reviews. Request documentation like COAs (Certificates of Analysis) to validate product quality.

Q: Do Losartan Potassium (CAS 124750-99-8) factories offer custom synthesis services?

A: Some factories provide custom synthesis or bulk manufacturing based on client requirements. Confirm their capabilities, lead times, and minimum order quantities (MOQs) beforehand.

Q: How do Losartan Potassium (CAS 124750-99-8) suppliers ensure product stability during shipping?

A: Reputable suppliers use temperature-controlled packaging and comply with ICH stability guidelines. They also provide storage recommendations to maintain product integrity during transit.

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