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Samh . 02, 2024 21:52 Back to list

china 3-chloropyridine cas 626-60-8



Understanding 3-Chloropyridine Properties, Applications, and Safety


3-Chloropyridine, with the CAS number 626-60-8, is a heterocyclic organic compound that has garnered significant attention in various sectors, particularly in the field of pharmaceuticals and agrochemicals. This compound is characterized by a pyridine ring substituted with a chlorine atom at the third position, hence its name.


Chemical Properties

3-Chloropyridine has a molecular formula of C5H4ClN, and it possesses interesting physical and chemical properties. The compound is a colorless to light yellow liquid with a distinctive, pungent odor. It has a boiling point of around 145 °C and a melting point of approximately -9 °C. This compound is soluble in organic solvents such as alcohol and ether, but it has limited solubility in water. The presence of the chlorine atom in the pyridine ring influences its reactivity, making it a valuable intermediate in various chemical reactions.


Production and Synthesis


The synthesis of 3-chloropyridine can be accomplished through several methods. A common approach involves the chlorination of pyridine using chlorine gas or other chlorinating agents. This reaction needs to be carefully controlled to avoid excessive chlorination, which might lead to unwanted by-products. Advanced techniques such as nucleophilic substitution reactions with chlorinated reagents are also utilized to produce 3-chloropyridine efficiently.


Applications


china 3-chloropyridine cas 626-60-8

china 3-chloropyridine cas 626-60-8

One of the most significant applications of 3-chloropyridine is in the pharmaceutical industry. It serves as a crucial intermediate in the synthesis of various drugs, including those used to treat fungal infections, hypertension, and other critical medical conditions. The compound’s ability to enhance the biological activity of functional groups makes it a versatile building block in drug design.


In addition to its pharmaceutical uses, 3-chloropyridine plays a vital role in the agrochemical sector. It is often utilized in the production of herbicides and pesticides, helping to optimize agricultural yields and protect crops from pests and diseases. The compound's structural properties allow for the development of novel agrochemical products that provide effective solutions for modern agriculture.


Safety Considerations


While 3-chloropyridine is a valuable compound, it is essential to consider safety and environmental implications. The compound can be hazardous upon exposure, causing skin and eye irritation, and its inhalation may lead to respiratory issues. Therefore, it is crucial for individuals working with 3-chloropyridine to follow appropriate safety protocols, including the use of personal protective equipment (PPE) such as gloves, goggles, and respirators.


Releases into the environment should be controlled, as chlorinated compounds have the potential to be toxic to aquatic life. Regulatory guidelines must be adhered to in the production and disposal of this chemical to minimize environmental impact.


Conclusion


In conclusion, 3-chloropyridine is a crucial compound within the realms of pharmaceuticals and agrochemicals, valued for its versatility and reactivity. Understanding its properties, applications, and the necessary safety measures is pivotal for anyone involved in its production or use. Continued research and development in this field promise to unlock even more potential applications, further solidifying 3-chloropyridine's role in modern science and industry.


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