Isopropyl Acetoacetate An Overview and Supplier Insights

Isopropyl acetoacetate, with the CAS number 542-08-5, is a significant organic compound that has garnered attention in various industries, particularly in the fields of pharmaceuticals, agrochemicals, and synthetic organic chemistry. Its unique chemical properties make it a valuable intermediate for the synthesis of various bioactive compounds, including pharmaceuticals, dyes, and other industrial chemicals. In this article, we will explore the characteristics, applications, and potential suppliers of isopropyl acetoacetate.

Chemical Properties

Isopropyl acetoacetate is classified as a beta-keto ester, characterized by the presence of both an ester and a ketone functional group in its structure. This compound is typically a colorless to pale yellow liquid with a fruity odor, making it not only functional but also pleasant in aroma. Its molecular formula is C8H14O3, and it possesses a molecular weight of 158.19 g/mol. With a boiling point of approximately 162-164°C and a density of around 1.045 g/cm³, isopropyl acetoacetate is soluble in organic solvents like alcohol, ether, and acetone, while being only slightly soluble in water.

Applications

The versatility of isopropyl acetoacetate can be attributed to its ability to undergo various chemical reactions. Some of its primary applications include

1. Pharmaceuticals Isopropyl acetoacetate is frequently used as an intermediate in the synthesis of a variety of pharmaceutical compounds. Its reactive beta-keto ester functionality allows for condensation reactions, enabling the formation of more complex molecules with pharmacological activities. It has been utilized in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), antibacterial agents, and other therapeutic agents.

2. Agrochemicals In the agricultural sector, isopropyl acetoacetate serves as a building block for the production of herbicides and insecticides. Its role in synthesizing agrochemicals contributes to enhancing crop yields and protecting plants from pests and diseases.

3. Flavor and Fragrance Industry Due to its fruity odor, isopropyl acetoacetate is used in the formulation of flavoring agents and fragrances. Its pleasing characteristics make it an attractive ingredient in food additives and cosmetic products.

4. Research and Development In academic and industrial laboratories, isopropyl acetoacetate is often employed as a reagent in organic synthesis and as a standard in analytical chemistry. Its ability to act as a precursor for complex organic molecules makes it essential in R&D.

Finding Reliable Suppliers

When it comes to sourcing isopropyl acetoacetate, it is crucial to find a reliable supplier who offers high-quality products that meet industry standards. Here are some tips for locating reputable suppliers

1. Online Marketplaces Platforms like Alibaba, ChemSpider, and various chemical marketplaces can connect you with manufacturers and distributors of isopropyl acetoacetate. Ensure you check the supplier’s ratings and reviews to gauge their reliability.

2. Industry Associations Membership in chemical industry associations can provide access to a network of reliable suppliers. These organizations often conduct background checks, ensuring that their members adhere to safety and quality standards.

3. Trade Shows and Conferences Attending chemical trade shows and industry conferences can be an excellent way to meet suppliers face-to-face. These events provide opportunities to evaluate products, negotiate contracts, and establish long-term relationships.

4. Local Chemical Distributors Depending on your location, local chemical supply companies may stock isopropyl acetoacetate. Building relationships with these suppliers can help ensure quick access to needed materials.

Conclusion

Isopropyl acetoacetate is a versatile compound with wide-ranging applications across various industries. Its importance in the synthesis of pharmaceutical intermediates, agrochemicals, and specialized formulations cannot be overstated. By understanding its properties, uses, and sourcing possibilities, industries can effectively leverage this compound to innovate and drive their businesses forward. When searching for suppliers, diligence in research and consideration of supplier reputation can lead to successful procurement and application of isopropyl acetoacetate.