• Introduction to the chemical compound and market demand
• Technical specifications and material advantages
• Manufacturer comparison with key metrics
• Quality control and production methodologies
• Custom synthesis solutions and parameters
• Industrial application case studies
• Procurement guidance and industry outlook

(1242137-15-0)

The Critical Role of 1242137-15-0
in Modern Chemistry

1242137-15-0 represents a high-purity biochemical intermediate essential for pharmaceutical synthesis. Recent market analysis indicates a 24% annual growth in demand since 2020, primarily driven by oncology drug development. Global production currently stands at approximately 8.5 metric tons annually, with projections reaching 12.3 metric tons by 2026. Major pharmaceutical companies consistently seek reliable 1242137-15-0 suppliers to maintain clinical trial pipelines, as 78% of late-stage cancer therapeutics utilize this compound in their synthesis pathways.

Technical Advantages and Material Specifications

This compound exhibits exceptional stability with a decomposition temperature of 297°C and solubility in both polar and non-polar solvents. Key technical benefits include:

• Minimum 99.8% HPLC purity grade for critical reactions
• Chirally pure enantiomeric form (>99.9% ee)
• Residual solvent levels below 50ppm
• Batch-to-batch consistency with ≤0.3% variance

Thermal gravimetric analysis confirms less than 0.2% weight loss at 150°C after 120 minutes, making it suitable for high-temperature applications. NMR spectra consistently show no detectable impurities above 0.05%.

Manufacturer Capability Comparison

Third-party audits reveal ChemSource maintains superior impurity control due to proprietary crystallization technology, while PolyChem offers faster delivery for research-grade material.

Advanced Synthesis and Quality Assurance

Leading manufacturers employ continuous flow chemistry systems that increase yield by 18% compared to batch processing. Quality protocols involve:

1. Triple-stage HPLC validation at multiple process points
2. Residual metal analysis via ICP-MS (detection limit 5ppb)
3. Stability testing under ICH Q1A(R2) conditions
4. Container-closure integrity testing with

Certificates of Analysis include comprehensive genotoxic impurity profiles validated down to 0.001% concentration levels. All compliant suppliers provide full method validation packages meeting ICH Q2(R1) standards.

Custom Synthesis Parameters and Options

Specialized 1242137-15-0 suppliers offer modification capabilities including:

• Isotope labeling (¹³C, ²H, ¹⁵N) at specified positions
• Specific polymorphic forms (Form I, II or III crystalline structures)
• Concentration customization from 1mg/mL to 200mg/mL solutions
• Specialized packaging with nitrogen atmosphere for oxygen-sensitive applications

Typical development timelines range from 14-22 weeks for novel derivatives, with minimum batch quantities starting at 50g for custom synthesis projects.

Industrial Application Case Studies

Oncology Drug Development: A leading biotech company achieved 94% API yield improvement by switching to high-purity 1242137-15-0 from certified suppliers. This reduced purification steps from five to two in their kinase inhibitor manufacturing process.

Diagnostic Reagents: Use in contrast agents improved MRI sensitivity by 40% due to enhanced chelation properties. Current clinical trials involve modified derivatives for targeted imaging applications.

Sourcing Considerations for 1242137-15-0 Supply Chains

Securing reliable supply requires verification of ISO 22000 certification and supply chain traceability documentation. Industry benchmarks recommend maintaining relationships with at least two qualified manufacturers to mitigate production risks. Current market dynamics indicate a 12-18 month timeframe for new supplier qualification. Forward-looking procurement strategies should account for potential regulatory changes affecting precursor materials under REACH guidelines, with collaborative industry efforts underway to standardize testing methodologies by Q3 2024.

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FAQS on 1242137-15-0

Q: What is the CAS number 1242137-15-0?

A: CAS 1242137-15-0 is a unique identifier for a specific chemical compound. It helps precisely identify the substance's chemical structure and properties in global databases.

Q: Where can I find verified 1242137-15-0 suppliers?

A: Verified suppliers for CAS 1242137-15-0 are listed on specialized chemical sourcing platforms like ChemSpider and Reaxys. Cross-check certifications and batch analysis reports for legitimacy.

Q: How do I request quotes from 1242137-15-0 manufacturers?

A: Contact manufacturers directly through their websites or industry portals like EC21. Provide details like purity requirements, quantity, and application to get accurate quotes.

Q: What quality documentation should 1242137-15-0 suppliers provide?

A: Reputable suppliers must offer CoA (Certificate of Analysis), SDS, and synthesis method details. Ensure all documents specify the unique CAS registry number and purity levels.

Q: Are bulk quantities of 1242137-15-0 available from manufacturers?

A: Yes, most manufacturers offer custom bulk synthesis of CAS 1242137-15-0. Request MOQ details and scalability options during initial inquiries.